Dallas Buyers Club

Dallas Buyers Club is a 2013 American biographical drama film, cowritten by Craig Borten and Melisa Wallack, directed by JeanMarc Valle. Ron Woodroof Matthew McConaughey was an AIDS patient diagnosed in the mid 1980s when HIVAIDS treatments were underresearched, while the disease was not understood and highly stigmatized. As part of the experimental AIDS treatment movement, he smuggled unapproved pharmaceutical drugs into Texas for treating his symptoms, and distributed them to fellow people with AIDS by establishing the Dallas Buyers Club while facing opposition from the Food and Drug Administration FDA. Two fictional supporting characters, Dr. Eve Saks Jennifer Garner, and Rayon Jared Leto, were composite roles created from the writers interviews with transgender AIDS patients, activists, and doctors.

In 1985, Dallas electrician and rodeo cowboy Ron Woodroof is diagnosed with AIDS and givendays to live. He initially refuses to accept the diagnosis, but remembers having unprotected sex with an intravenous drugusing prostitute. He is soon ostracized by family and friends, gets fired from his job, and is eventually evicted from his home. At the hospital, he is tended to by Dr. Eve Saks, who tells him that they are testing a drug called zidovudine AZT, an antiretroviral drug which is thought to prolong the life of AIDS patientsand is the only drug approved by the Food and Drug Administration FDA for testing on humans. Saks informs him that in the clinical trials, half the patients receive the drug and the other half are given a placebo, as this is the only way they can determine if the drug is working.Woodroof bribes a hospital worker to get him the AZT. As soon as he begins taking it, he finds his health deteriorating exacerbated by his cocaine use. When he returns to the hospital, he meets Rayon, a drug addicted, HIVpositive trans woman, toward whom he is hostile. As his health worsens, he drives to a Mexican hospital to get more AZT. Dr. Vass, who has had his American medical license revoked, tells him that the AZT is poisonous and kills every cell it comes into contact with. He instead prescribes ddC and the protein peptide T, which are not approved in the US. Three months later, Woodroof finds his health much improved. It occurs to him that he could make money by importing the drugs and selling them to other HIVpositive patients. Since the drugs are not illegal, he is able to get them over the border by masquerading as a priest and swearing that they are for personal use. Meanwhile, Dr. Saks also begins to notice the negative effects of AZT, but is told by her supervisor Dr. Sevard that it cannot be discontinued. ........

Source: Wikipedia